Scr

• Description: 4.5 S RNA
  
  

Gene name	scr
Synonyms
Essential	no
Product	small cytoplasmic RNA (scRNA, 4.5S RNA), signal recognition particle-like (SRP) component
Function	presecretory protein translocation
Immediate neighbours	yaaJ, dnaX
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

• Structure:

The RNA

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

Extended information on the RNA

• Kinetic information

• Interactions: Scr-Ffh

• Localization

Database entries

• Structure:

Expression and regulation

• Operon: yaaJ-scr, scr

• Sigma factor: SigA (both promoters)

• Regulation:

• Regulatory mechanism:

• Additional information: transcribed as 354 nt precursor, cleaved at the 5' end by RNase III and at the 3' site by RNase J1 to yield a 275 nt molecule, final trimming to 271 nt sc RNA by RNase PH PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage

References

1. Yao, S., Blaustein, J. B. & Bechhofer, D. H. (2007). Processing of Bacillus subtilis small cytoplasmic RNA: evidence for an additional endonuclease cleavage site. Nucleic Acids Res. 35:4464-4473. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed