Difference between revisions of "OdhB"
| Line 38: | Line 38: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU19360 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 85: | Line 85: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P16263 P16263] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P16263 P16263] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU19360] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.3.1.61 2.3.1.61] 1 | * '''E.C. number:''' [http://www.expasy.org/enzyme/2.3.1.61 2.3.1.61] 1 | ||
Revision as of 09:48, 3 June 2009
- Description: 2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit)
| Gene name | odhB |
| Synonyms | citM |
| Essential | yes PubMed |
| Product | 2-oxoglutarate dehydrogenase complex
(dihydrolipoamide transsuccinylase, E2 subunit) |
| Function | TCA cycle |
| MW, pI | 45 kDa, 4.859 |
| Gene length, protein length | 1251 bp, 417 aa |
| Immediate neighbours | odhA, yocS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU19360
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Succinyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-succinyldihydrolipoyl)lysine (according to Swiss-Prot)
- Protein family: sodium:bile acid symporter family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed
Database entries
- Structure:
- Swiss prot entry: P16263
- KEGG entry: [3]
- E.C. number: 2.3.1.61 1
Additional information
Expression and regulation
- Sigma factor: SigA
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
- Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed
- Kobayashi et al. (2003) Essential Bacillus subtilis genes. Proc. Natl. Acad. Sci. USA 100: 4678-4683. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
