Difference between revisions of "Sr1"
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=== Basic information === | === Basic information === | ||
| − | * ''' | + | * '''Locus tag:''' |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
Revision as of 13:09, 2 June 2009
- Description: small regulatory RNA controlling AhrC expression
| Gene name | sr1 |
| Synonyms | ykzW |
| Essential | no |
| Product | small regulatory RNA/ regulatory peptide |
| Function | control of arginine metabolism |
| MW, pI | 4.4 kDa, 3.89 |
| Gene length, protein length | 205 bp (RNA), 120 bp (ORF), 39 aa |
| Immediate neighbours | slp, speA |
| Gene sequence | |
Genetic context 
| |
Contents
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
Additional information
Located between the slp and speA genes.
The RNA
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hybridizes to ahrC mRNA and inhibits AhrC translation. PubMed
Extended information on the RNA
- Kinetic information
- Localization
Database entries
- Structure:
Additional information
Information on the structure of the RNA can be found in Heidrich et al., 2006
The peptide
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: the peptide is conserved in bacilli
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Operon: sr1 PubMed
- Regulatory mechanism: transcription repression PubMed
- Additional information:
Biological materials
- Mutant: 168 sr1::cat, available in Brantl lab
- Expression vector:
- lacZ fusion:
Labs working on this gene/protein
Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage
Your additional remarks
References
- Licht et al. (2005) Implication of CcpN in the regulation of a novel untranslated RNA (SR1) in Bacillus subtilis. Mol. Microbiol. 58: 189-206. PubMed
- Heidrich et al. (2006) The small untranslated RNA SR1 from the Bacillus subtilis genome is involved in the regulation of arginine catabolism. Mol. Microbiol. 62: 520-536. PubMed
- Heidrich et al. (2007) In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA. Nucl. Acids Res. 35: 4331-4346. PubMed
