Difference between revisions of "Sr1"
| Line 35: | Line 35: | ||
=The gene= | =The gene= | ||
| − | == Basic information == | + | === Basic information === |
* '''Coordinates:''' | * '''Coordinates:''' | ||
| − | ==Phenotypes of a mutant == | + | ===Phenotypes of a mutant === |
| − | == Database entries == | + | === Database entries === |
* '''DBTBS entry:''' | * '''DBTBS entry:''' | ||
| − | == Additional information== | + | === Additional information=== |
Located between the ''[[slp]]'' and ''[[speA]]'' genes. | Located between the ''[[slp]]'' and ''[[speA]]'' genes. | ||
| Line 51: | Line 51: | ||
=The RNA= | =The RNA= | ||
| − | == Basic information/ Evolution == | + | === Basic information/ Evolution === |
* '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[ahrC]]'' mRNA and inhibits AhrC translation. [http://www.ncbi.nlm.nih.gov/sites/entrez/17020585 PubMed] | * '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[ahrC]]'' mRNA and inhibits AhrC translation. [http://www.ncbi.nlm.nih.gov/sites/entrez/17020585 PubMed] | ||
| − | == Extended information on the RNA== | + | === Extended information on the RNA=== |
* '''Kinetic information''' | * '''Kinetic information''' | ||
| Line 63: | Line 63: | ||
* '''Localization''' | * '''Localization''' | ||
| − | == Database entries == | + | === Database entries === |
* '''Structure''': | * '''Structure''': | ||
| − | == Additional information== | + | === Additional information=== |
Information on the structure of the RNA can be found in [http://www.ncbi.nlm.nih.gov/pubmed/17020585?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Heidrich ''et al''., 2006 ] | Information on the structure of the RNA can be found in [http://www.ncbi.nlm.nih.gov/pubmed/17020585?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Heidrich ''et al''., 2006 ] | ||
Revision as of 13:59, 17 December 2008
- Description: small regulatory RNA controlling AhrC expression
| Gene name | sr1 |
| Synonyms | |
| Essential | no |
| Product | small regulatory RNA |
| Function | control of arginine metabolism |
| pI, MW | not applicable |
| Gene length, protein length | 205 bp, not applicable |
| Immediate neighbours | slp, speA |
| Gene sequence (+200bp) | |
| Genetic context File:GenE context.gif | |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry:
Additional information
Located between the slp and speA genes.
The RNA
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hybridizes to ahrC mRNA and inhibits AhrC translation. PubMed
Extended information on the RNA
- Kinetic information
- Localization
Database entries
- Structure:
Additional information
Information on the structure of the RNA can be found in Heidrich et al., 2006
Expression and regulation
- Operon: sr1 PubMed
- Regulatory mechanism: transcription repression PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- Antibody:
Labs working on this gene/protein
Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage
Your additional remarks
References
- Licht et al. (2005) Implication of CcpN in the regulation of a novel untranslated RNA (SR1) in Bacillus subtilis. Mol. Microbiol. 58: 189-206. PubMed
- Heidrich et al. (2006) The small untranslated RNA SR1 from the Bacillus subtilis genome is involved in the regulation of arginine catabolism. Mol. Microbiol. 62: 520-536. PubMed
- Heidrich et al. (2007) In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA. Nucl. Acids Res. 35: 4331-4346. PubMed
