CBS domain

This domain is found in several membrane proteins.

• For more information, see InterPro
• Some CBS domain-containing proteins bind c-di-AMP PubMed

Proteins containing CBS domains

• AcuB
• CcpN
• GuaB
• OpuAA
• OpuBA
• OpuCA
• MgtE
• SpoIVFB
• YhdT
• YkuL
• YhcV
• YhdP
• YrkA
• YtoI
• YlbB
• YqhB
• YugS

Related SubtiWiki pages

• Targets of c-di-AMP

Important references

Jan Gundlach, Larissa Krüger, Christina Herzberg, Asan Turdiev, Anja Poehlein, Igor Tascón, Martin Weiss, Dietrich Hertel, Rolf Daniel, Inga Hänelt, Vincent T Lee, Jörg Stülke
Sustained sensing in potassium homeostasis: Cyclic di-AMP controls potassium uptake by KimA at the levels of expression and activity.
J Biol Chem: 2019, 294(24);9605-9614
[PubMed:31061098] [WorldCat.org] [DOI] (I p)

June Ereño-Orbea, Iker Oyenarte, Luis Alfonso Martínez-Cruz
CBS domains: Ligand binding sites and conformational variability.
Arch Biochem Biophys: 2013, 540(1-2);70-81
[PubMed:24161944] [WorldCat.org] [DOI] (I p)

Alexander A Baykov, Heidi K Tuominen, Reijo Lahti
The CBS domain: a protein module with an emerging prominent role in regulation.
ACS Chem Biol: 2011, 6(11);1156-63
[PubMed:21958115] [WorldCat.org] [DOI] (I p)

Esther Biemans-Oldehinkel, Nik A B N Mahmood, Bert Poolman
A sensor for intracellular ionic strength.
Proc Natl Acad Sci U S A: 2006, 103(28);10624-9
[PubMed:16815971] [WorldCat.org] [DOI] (P p)

Bruce E Kemp
Bateman domains and adenosine derivatives form a binding contract.
J Clin Invest: 2004, 113(2);182-4
[PubMed:14722609] [WorldCat.org] [DOI] (P p)