Difference between revisions of "LutR"
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvfI_3509831_3510490_-1 lutR] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvfI_3509831_3510490_-1 lutR] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|25031425}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | <pubmed> 24196425, 19201793 </pubmed> | + | <pubmed> 24196425, 19201793 25031425 18604637</pubmed> |
| − | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:03, 18 July 2014
- Description: transcriptional repressor (GntR family) of the lutA-lutB-lutC operon
| Gene name | lutR |
| Synonyms | yvfI |
| Essential | no |
| Product | transcriptional repressor, (GntR family) |
| Function | control of lactate utilization |
| Gene expression levels in SubtiExpress: lutR | |
| Metabolic function and regulation of this protein in SubtiPathways: lutR | |
| MW, pI | 19 kDa, 4.845 |
| Gene length, protein length | 525 bp, 175 aa |
| Immediate neighbours | lacR, lutP |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The LutR regulon:
The gene
Basic information
- Locus tag: BSU34180
Phenotypes of a mutant
Database entries
- BsubCyc: BSU34180
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed
- Protein family: GntR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: lactate acts as molecular inducer PubMed
Database entries
- BsubCyc: BSU34180
- Structure:
- UniProt: O07007
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: TEK1 lutR::Tn10::spc PubMed
- Expression vector: pQE60-lutR (His-tag) PubMed
- lacZ fusion: TEK7 lutR::lacZ::erm PubMed
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Ayten Katatas, Istanbul Technical University, Istanbul, Turkey [3]
Your additional remarks
References
Kuo-Chin Chiu, Chen-Jyun Lin, Gwo-Chyuan Shaw
Transcriptional regulation of the l-lactate permease gene lutP by the LutR repressor of Bacillus subtilis RO-NN-1.
Microbiology (Reading): 2014, 160(Pt 10);2178-2189
[PubMed:25031425]
[WorldCat.org]
[DOI]
(I p)
Öykü İrigül-Sönmez, Türkan E Köroğlu, Büşra Öztürk, Ákos T Kovács, Oscar P Kuipers, Ayten Yazgan-Karataş
In Bacillus subtilis LutR is part of the global complex regulatory network governing the adaptation to the transition from exponential growth to stationary phase.
Microbiology (Reading): 2014, 160(Pt 2);243-260
[PubMed:24196425]
[WorldCat.org]
[DOI]
(I p)
Yunrong Chai, Roberto Kolter, Richard Losick
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
J Bacteriol: 2009, 191(8);2423-30
[PubMed:19201793]
[WorldCat.org]
[DOI]
(I p)
Türkan Ebru Köroğlu, Günseli Kurt-Gür, Emine Canan Unlü, Ayten Yazgan-Karataş
The novel gene yvfI in Bacillus subtilis is essential for bacilysin biosynthesis.
Antonie Van Leeuwenhoek: 2008, 94(3);471-9
[PubMed:18604637]
[WorldCat.org]
[DOI]
(P p)
