Difference between revisions of "ComGE"
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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** [[ComGB]]-[[ComGE]] {{PubMed|15083159}} | ** [[ComGB]]-[[ComGE]] {{PubMed|15083159}} | ||
** [[ComC]]-[[ComGE]] {{PubMed|9723928}} | ** [[ComC]]-[[ComGE]] {{PubMed|9723928}} | ||
| + | ** [[ComGD]]-[[ComGE]] {{PubMed|24164455}} | ||
| + | ** [[ComGE]]-[[ComGG]] {{PubMed|24164455}} | ||
* '''[[Localization]]:''' cell surface [http://www.ncbi.nlm.nih.gov/pubmed/9723928 PubMed] | * '''[[Localization]]:''' cell surface [http://www.ncbi.nlm.nih.gov/pubmed/9723928 PubMed] | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comGE_2556921_2557268_-1 comGE] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comGE_2556921_2557268_-1 comGE] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|2507524}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2507524}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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<pubmed> 15083159 </pubmed> | <pubmed> 15083159 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>9422590,9723928,11814663,2507524,12107147 8196543 </pubmed> | + | <pubmed>9422590,9723928,11814663,2507524,12107147 8196543 24164455</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:14, 16 March 2014
- Description: DNA transport machinery, minor pseudopilin
| Gene name | comGE |
| Synonyms | |
| Essential | no |
| Product | minor pseudopilin |
| Function | genetic competence, DNA uptake |
| Gene expression levels in SubtiExpress: comGE | |
| Interactions involving this protein in SubtInteract: ComGE | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 13 kDa, 5.238 |
| Gene length, protein length | 345 bp, 115 aa |
| Immediate neighbours | comGF, comGD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization: cell surface PubMed
Database entries
- Structure:
- UniProt: P25957
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- repressed by casamino acids PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159]
[WorldCat.org]
[DOI]
(P p)
Original publications
Jessica M Mann, Valerie J Carabetta, Ileana M Cristea, David Dubnau
Complex formation and processing of the minor transformation pilins of Bacillus subtilis.
Mol Microbiol: 2013, 90(6);1201-15
[PubMed:24164455]
[WorldCat.org]
[DOI]
(I p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
Hanne Jarmer, Randy Berka, Steen Knudsen, Hans H Saxild
Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions.
FEMS Microbiol Lett: 2002, 206(2);197-200
[PubMed:11814663]
[WorldCat.org]
[DOI]
(P p)
Y S Chung, F Breidt, D Dubnau
Cell surface localization and processing of the ComG proteins, required for DNA binding during transformation of Bacillus subtilis.
Mol Microbiol: 1998, 29(3);905-13
[PubMed:9723928]
[WorldCat.org]
[DOI]
(P p)
Y S Chung, D Dubnau
All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.
J Bacteriol: 1998, 180(1);41-5
[PubMed:9422590]
[WorldCat.org]
[DOI]
(P p)
D van Sinderen, A ten Berge, B J Hayema, L Hamoen, G Venema
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis.
Mol Microbiol: 1994, 11(4);695-703
[PubMed:8196543]
[WorldCat.org]
[DOI]
(P p)
M Albano, R Breitling, D A Dubnau
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.
J Bacteriol: 1989, 171(10);5386-404
[PubMed:2507524]
[WorldCat.org]
[DOI]
(P p)
