Difference between revisions of "HtrC"
| Line 113: | Line 113: | ||
** expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | ** expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | ||
** ''htrC'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | ** ''htrC'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed] | ||
| + | ** ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' is induced upon deletion of ''[[htrA]]'' and ''[[htrB]]'' {{PubMed|24115457}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 140: | Line 141: | ||
<pubmed>21326199 </pubmed> | <pubmed>21326199 </pubmed> | ||
== Original publications == | == Original publications == | ||
| − | <pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 </pubmed> | + | <pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 24115457 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:16, 15 January 2014
- Description: similar to quality control membrane serine protease HtrA
| Gene name | htrC |
| Synonyms | yycK, yyxA |
| Essential | no |
| Product | putative quality control membrane protease |
| Function | unknown |
| Gene expression levels in SubtiExpress: htrC | |
| MW, pI | 42 kDa, 5.315 |
| Gene length, protein length | 1200 bp, 400 aa |
| Immediate neighbours | yyzO, walJ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
proteolysis, sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40360
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase S1B family (according to Swiss-Prot)
- Paralogous protein(s): HtrA
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Interactions:
- HtrC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39668
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: for htrC: SigG PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Tim Clausen, Markus Kaiser, Robert Huber, Michael Ehrmann
HTRA proteases: regulated proteolysis in protein quality control.
Nat Rev Mol Cell Biol: 2011, 12(3);152-62
[PubMed:21326199]
[WorldCat.org]
[DOI]
(I p)
Original publications
