Difference between revisions of "GtaB"

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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* the inactivation of ''[[gtaB]]'' suppresses the poor and filametous growth of the ''[[yvcL]] [[zapA]]'' double mutant {{PubMed|24097947}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''  
 
* '''Modification:'''  
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** phosphorylated on ser/ thr/ tyr [http://www.ncbi.nlm.nih.gov/pubmed/16493705 PubMed]  
 
** phosphorylated on ser/ thr/ tyr [http://www.ncbi.nlm.nih.gov/pubmed/16493705 PubMed]  
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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=References=
 
=References=
  
<pubmed>8320212,2846750,22517742,16493705 11544224, </pubmed>
+
<pubmed>8320212,2846750,22517742,16493705 11544224,24097947 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:18, 21 December 2013

  • Description: UTP-glucose-1-phosphate uridylyltransferase, general stress protein

Gene name gtaB
Synonyms
Essential no
Product UTP-glucose-1-phosphate uridylyltransferase
Function biosynthesis of teichoic acid
Gene expression levels in SubtiExpress: gtaB
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 32 kDa, 4.913
Gene length, protein length 876 bp, 292 aa
Immediate neighbours mnaA, yvzH
Sequences Protein DNA DNA_with_flanks
Genetic context
GtaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GtaB expression.png















Categories containing this gene/protein

cell wall synthesis, lipid metabolism/ other, biosynthesis of cell wall components, general stress proteins (controlled by SigB), phosphoproteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU35670

Phenotypes of a mutant

  • the inactivation of gtaB suppresses the poor and filametous growth of the yvcL zapA double mutant PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose (according to Swiss-Prot)
  • Protein family: UDPGP type 2 family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Modification:
    • phosphorylated on Arg-76 PubMed
    • phosphorylated on ser/ thr/ tyr PubMed
  • Effectors of protein activity:

Database entries

  • Structure: 2E3D (from E. coli, 44% identity, 61% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References