Difference between revisions of "SpoIVB"
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| − | * '''Description:''' serine protease, cleaves [[SpoIVFA]], this results in pro-[[SigK]] processing/activation in the mother-cell, does also cleave [[CtpB]] <br/><br/> | + | * '''Description:''' serine protease, cleaves [[SpoIVFA]] to prepare it for [[CtpB]] cleavage, this results in pro-[[SigK]] processing/activation in the mother-cell, does also cleave [[CtpB]] <br/><br/> |
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* '''Catalyzed reaction/ biological activity:''' Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the N-terminus of SpoIVB (according to Swiss-Prot) | * '''Catalyzed reaction/ biological activity:''' Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the N-terminus of SpoIVB (according to Swiss-Prot) | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' PDZ protease {{PubMed|24243021}} |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
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* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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** [[SpoIVB]]-[[BofA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15292188 PubMed] | ** [[SpoIVB]]-[[BofA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15292188 PubMed] | ||
** [[BofC]]-[[SpoIVB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10931291 PubMed] | ** [[BofC]]-[[SpoIVB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10931291 PubMed] | ||
| + | ** [[SpoIVB]]-[[SpoIVFA]] {{PubMed|24243021}} | ||
| − | * '''[[Localization]]:''' | + | * '''[[Localization]]:''' |
| + | ** intracellular space between the mother cell and the forespore {{PubMed|24243021}} | ||
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVB_2519102_2520382_-1 spoIVB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVB_2519102_2520382_-1 spoIVB] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigF]] {{PubMed|15699190,9004507}}, [[SigG]] {{PubMed|15699190,9004507}} | + | * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|15699190,9004507}}, [[SigG]] {{PubMed|15699190,9004507}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | <pubmed>17493131 2106508 10931284,14526016,10931291,1900494,11418578, 15292188,9004507,12940997, 11741860,16497325,8755877 ,,15292188, 17557826 16818230 </pubmed> | + | <pubmed>17493131 2106508 10931284,14526016,10931291,1900494,11418578, 15292188,9004507,12940997, 11741860,16497325,8755877 ,24243021,15292188, 17557826 16818230 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:02, 3 December 2013
- Description: serine protease, cleaves SpoIVFA to prepare it for CtpB cleavage, this results in pro-SigK processing/activation in the mother-cell, does also cleave CtpB
| Gene name | spoIVB |
| Synonyms | |
| Essential | no |
| Product | serine protease |
| Function | control of SigK activation |
| Gene expression levels in SubtiExpress: spoIVB | |
| Interactions involving this protein in SubtInteract: SpoIVB | |
| MW, pI | 45 kDa, 8.842 |
| Gene length, protein length | 1275 bp, 425 aa |
| Immediate neighbours | spo0A, recN |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the N-terminus of SpoIVB (according to Swiss-Prot)
- Protein family: PDZ protease PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Effectors of protein activity:
- Localization:
- intracellular space between the mother cell and the forespore PubMed
Database entries
- Structure:
- UniProt: P17896
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIVB PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Simon Cutting, London, UK homepage
Your additional remarks
References
