Difference between revisions of "RNA polymerase"
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=='''The enzyme responsible for [[transcription]]'''== | =='''The enzyme responsible for [[transcription]]'''== | ||
| + | * As an important difference as compared to the ''E. coli'' enzyme, the ''B. subtilis'' RNA polymerase has a strong preference for G as first nucleotides in transcripts {{PubMed|23761441}} | ||
==Components of the RNA polymerase== | ==Components of the RNA polymerase== | ||
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<pubmed> 12732296 12581657 11297923 19735077 </pubmed> | <pubmed> 12732296 12581657 11297923 19735077 </pubmed> | ||
=== Important original publications === | === Important original publications === | ||
| − | <pubmed> 21350489 21515770 22333917,20817769,20724389,21710567</pubmed> | + | <pubmed> 21350489 21515770 22333917,20817769,20724389,21710567 23761441 </pubmed> |
Revision as of 15:10, 14 June 2013
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Contents
The enzyme responsible for transcription
- As an important difference as compared to the E. coli enzyme, the B. subtilis RNA polymerase has a strong preference for G as first nucleotides in transcripts PubMed
Components of the RNA polymerase
Core subunits
Sigma factors
- In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)
Small accessory subunits
Other interaction partners
- NusA: essential elongation factor
- GreA: resolves promoter proximal pausing of RNA polymerase PubMed
- CshA: DEAD-box RNA helicase PubMed
Temporary interaction partners
- Spx: transcription regulator, interacts with RpoA
- MgsR: transcription regulator orthologous to Spx, interacts with RpoA
- Btr: transcription activator PubMed
- YlyA: modulates SigG-dependent transcription PubMed
- Additional interaction partners of the RNA polymerase (no specific subunit specified)
Back to protein-protein interactions
References
Reviews
The structure of RNA polymerase
Important original publications
