GerKA

• Description: nutrient receptor
  
  

Gene name	gerKA
Synonyms
Essential	no
Product	nutrient receptor
Function	germination response to the combination of glucose, fructose, aspartate, and KCl
Gene expression levels in SubtiExpress: gerKA
Interactions involving this protein in SubtInteract: GerKA
MW, pI	60 kDa, 5.206
Gene length, protein length	1632 bp, 544 aa
Immediate neighbours	gerKD, gerKC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU03700

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerABKA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • contains multiple membrane-spanning domains PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GerKA-GerKB-GerKC (tentative receptor complex) PubMed
  • GerKA is part of the germinosome in the spore inner membrane PubMed

• Localization:
  • outer surface of the inner spore membrane PubMed

Database entries

• Structure:

• UniProt: P49939

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerKA-gerKC-gerKB (according to DBTBS)

• Expression browser: gerKA PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed during sporulation (SigG, SpoVT) PubMed

• Regulatory mechanism:
  • SpoVT: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed