gerKC

gerKC
168

nutrient receptor

Locus
BSU_03710
Molecular weight
45.67 kDa
Isoelectric point
9.04
Protein length
407 aaSequenceBlast
Gene length
1224 bpSequenceBlast
Function
germination
Product
part of the putative nutrient-gated GerKA-GerKB-GerKC ion channel
Essential
no
Synonyms
gerKC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5903 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
421,734 → 422,957
The protein
Catalyzed reaction/ biological activity
the GerKA-GerKB-GerKC ion channel likely releases ions from the spore core in response to asparagine, glucose, fructose and K+ to trigger Germination, this requires the gerB locus PubMed
Protein family
GerABKC lipoprotein family (according to UniProt)
Structure
P49941 (AlphaFold)
Localization
spore inner membrane PubMed
Expression and Regulation
Operons
Genes
gerKA-gerKC-gerKB
Description
PubMed
Regulation
expressed during sporulation (SigG, SpoVT) PubMed
Regulatory mechanism
SpoVT: repression, PubMed, in spoVT regulon
Sigma factors
SigG: sigma factor, PubMed, in sigG regulon
Additional information
700 molecules are present per spore PubMed
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gerKA→gerKB

2025-03-26 19:30:03

Jstuelk

115

2621476d83b6d6d9772912d035f86d1791de6cd2

5744A84AC240BED93491E29AB72B18EEE120A73F

Biological materials
Mutant
BKE03710 (ΔgerKC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AAGCATGAGAACGGCTAATA,  downstream forward: _UP4_TAGGTCTGAAGAAAGGGGAA
BKK03710 (ΔgerKC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AAGCATGAGAACGGCTAATA,  downstream forward: _UP4_TAGGTCTGAAGAAAGGGGAA
References
Reviews
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Original Publications
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D5D4E1E182F972BEF6BB432A7FF25EF45F1F0D95

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Time of last update: 2025-04-02 03:38:29

Author of last update: Jstuelk