BofC

• Description: general stress protein, controls processing of pro-SigK by SpoIVFB
  
  

Gene name	bofC
Synonyms
Essential	no
Product	forespore regulator of the sigma-K checkpoint
Function	control of processing of pro-SigK by SpoIVFB
Gene expression levels in SubtiExpress: bofC
Interactions involving this protein in SubtInteract: BofC
MW, pI	19 kDa, 5.753
Gene length, protein length	510 bp, 170 aa
Immediate neighbours	ruvA, csbX
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control, sporulation proteins, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon, SigF regulon, SigG regulon

The gene

Basic information

• Locus tag: BSU27750

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • BofC-SpoIVB PubMed

• Localization:

Database entries

• Structure: 2BW2

• UniProt: O05391

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csbX-bofC PubMed

• Expression browser: bofC PubMed

• Sigma factor: SigF PubMed, SigG PubMed, SigB PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG) PubMed
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: