Difference between revisions of "ComN"
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=== Additional information=== | === Additional information=== | ||
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| − | |||
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=The protein= | =The protein= | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' post-transcriptional control of ''[[comEA]]'' expression [http://www.ncbi.nlm.nih.gov/sites/entrez/19028902 PubMed] | + | * '''Catalyzed reaction/ biological activity:''' |
| − | + | ** post-transcriptional control of ''[[comEA]]'' expression [http://www.ncbi.nlm.nih.gov/sites/entrez/19028902 PubMed] | |
| + | ** promotes the accumulation of its target ''[[comEA]]'' mRNA to septal and polar sites {{PubMed|22582279}} | ||
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** [[DivIVA]]-[[ComN]] {{PubMed|22582279}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** cell | + | ** localizes to the division site and cell poles in a [[DivIVA]] dependent fashion {{PubMed|22582279}} |
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | <pubmed>19028902, | + | <pubmed>19028902,22582279, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:50, 23 May 2012
- Description: mediates post-transcriptional control of comE operon expression
| Gene name | comN |
| Synonyms | yrzD |
| Essential | no |
| Product | post-transcriptional regulator of comE expression |
| Function | regulation of competence and DNA uptake |
| MW, pI | 11 kDa, 4.622 |
| Gene length, protein length | 294 bp, 98 aa |
| Immediate neighbours | secDF, spoVB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
genetic competence, membrane proteins
This gene is a member of the following regulons
The ComN regulon: comEA-comEB-comEC
The gene
Basic information
- Locus tag: BSU27660
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32049
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Valquiria Tiago dos Santos, Alexandre W Bisson-Filho, Frederico J Gueiros-Filho
DivIVA-mediated polar localization of ComN, a posttranscriptional regulator of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3661-9
[PubMed:22582279]
[WorldCat.org]
[DOI]
(I p)
Mitsuo Ogura, Teruo Tanaka
The Bacillus subtilis late competence operon comE is transcriptionally regulated by yutB and under post-transcription initiation control by comN (yrzD).
J Bacteriol: 2009, 191(3);949-58
[PubMed:19028902]
[WorldCat.org]
[DOI]
(I p)
