ComN

• Description: mediates post-transcriptional control of comE operon expression
  
  

Gene name	comN
Synonyms	yrzD
Essential	no
Product	post-transcriptional regulator of comE expression
Function	regulation of competence and DNA uptake
MW, pI	11 kDa, 4.622
Gene length, protein length	294 bp, 98 aa
Immediate neighbours	secDF, spoVB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

genetic competence, membrane proteins

The gene

Basic information

• Locus tag: BSU27660

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Additional information

Expression

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: post-transcriptional control of comEA expression PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32049

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Teruo Tanaka
The Bacillus subtilis late competence operon comE is transcriptionally regulated by yutB and under post-transcription initiation control by comN (yrzD).
J Bacteriol: 2009, 191(3);949-58
[PubMed:19028902] [WorldCat.org] [DOI] (I p)