Difference between revisions of "ZnuC"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || zinc uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || zinc uptake | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ZnuC ZnuC] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]''' | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 693 bp, 231 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 693 bp, 231 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[znuA]]'', ''[[znuB]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12080]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12080]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 50: | Line 50: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | ** reduced genetic competence, can be rescued by the addition of excess zinc {{PubMed|21813502}} | |
| + | ** reduced expression of the ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' operon {{PubMed|21813502}} | ||
=== Database entries === | === Database entries === | ||
| Line 58: | Line 59: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 84: | Line 83: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[ | + | * '''Interactions:''' [[ZnuA]]-[[ZnuB]]-[[ZnuC]] {{PubMed|10092453}} |
| − | * '''Localization:''' associated to the membrane (via [[ | + | * '''Localization:''' associated to the membrane (via [[ZnuB]]) {{PubMed|10092453}} |
=== Database entries === | === Database entries === | ||
| Line 102: | Line 101: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[ | + | * '''Operon:''' ''[[znuA]]-[[znuC]]-[[znuB]]'' {{PubMed|9811636}} |
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12426338}} | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12426338}} | ||
| Line 134: | Line 133: | ||
=References= | =References= | ||
| − | <pubmed>12426338,9811636,10092453,,12426338, </pubmed> | + | <pubmed>12426338,9811636,10092453, 21813502,12426338, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:20, 5 August 2011
- Description: ABC transporter for zinc (ATP-binding protein)
| Gene name | ycdI |
| Synonyms | |
| Essential | no |
| Product | ABC transporter for zinc (ATP-binding protein) |
| Function | zinc uptake |
| Interactions involving this protein in SubtInteract: ZnuC | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 26 kDa, 8.198 |
| Gene length, protein length | 693 bp, 231 aa |
| Immediate neighbours | znuA, znuB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
ABC transporters, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU02860
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ABC transporter domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34946
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mitsuo Ogura
ZnuABC and ZosA zinc transporters are differently involved in competence development in Bacillus subtilis.
J Biochem: 2011, 150(6);615-25
[PubMed:21813502]
[WorldCat.org]
[DOI]
(I p)
Ahmed Gaballa, Tao Wang, Rick W Ye, John D Helmann
Functional analysis of the Bacillus subtilis Zur regulon.
J Bacteriol: 2002, 184(23);6508-14
[PubMed:12426338]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
A Gaballa, J D Helmann
Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis.
J Bacteriol: 1998, 180(22);5815-21
[PubMed:9811636]
[WorldCat.org]
[DOI]
(P p)
