Difference between revisions of "ComC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || genetic transformation | |style="background:#ABCDEF;" align="center"|'''Function''' || genetic transformation | ||
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+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 9.843 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 9.843 |
Revision as of 13:41, 11 December 2010
- Description: late competence gene required for processing and translocation of ComGC, ComGD, ComGE and ComGG PubMed
Gene name | comC |
Synonyms | |
Essential | no |
Product | processing protease |
Function | genetic transformation |
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
MW, pI | 26 kDa, 9.843 |
Gene length, protein length | 744 bp, 248 aa |
Immediate neighbours | spoIIB, folC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
genetic competence, protein secretion, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28070
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to Swiss-Prot)
- Protein family: peptidase A24 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P15378
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: comC PubMed
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References