Difference between revisions of "CheW"
| Line 1: | Line 1: | ||
| − | * '''Description:''' modulation of [[CheA]] activity in response to attractants <br/><br/> | + | * '''Description:''' modulation of [[CheA]] activity in response to attractants, scaffold protein: facilitates coupling between [[CheA]] and receptors <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 38: | Line 38: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | * ''[[cheV]] [[cheW]]'' double mutants exhibit complete loss of chemotaxis {{PubMed|21098025}} | |
=== Database entries === | === Database entries === | ||
| Line 59: | Line 59: | ||
* '''Protein family:''' | * '''Protein family:''' | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[CheV]] (N-terminal domain) |
=== Extended information on the protein === | === Extended information on the protein === | ||
| Line 75: | Line 75: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' cytoplasm (according to Swiss-Prot) | + | * '''Localization:''' |
| + | ** cytoplasm (according to Swiss-Prot) | ||
| + | ** predominantly present at the cell poles {{PubMed|21098025}} | ||
=== Database entries === | === Database entries === | ||
| Line 131: | Line 133: | ||
<pubmed> 20122866 </pubmed> | <pubmed> 20122866 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>,8169224,1601874,14731274,1624415,14651647, 9657996,8157612,15175317 17850253</pubmed> | + | <pubmed>,8169224,1601874,14731274,1624415,14651647, 9657996,8157612,15175317 17850253 21098025</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:30, 1 December 2010
- Description: modulation of CheA activity in response to attractants, scaffold protein: facilitates coupling between CheA and receptors
| Gene name | cheW |
| Synonyms | |
| Essential | no |
| Product | CheA modulator |
| Function | control of CheA activity |
| MW, pI | 17 kDa, 4.422 |
| Gene length, protein length | 468 bp, 156 aa |
| Immediate neighbours | cheA, cheC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU16440
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
Categories containing this gene/protein
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): CheV (N-terminal domain)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
- cytoplasm (according to Swiss-Prot)
- predominantly present at the cell poles PubMed
Database entries
- Structure:
- UniProt: P39802
- KEGG entry: [3]
- E.C. number:
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
