Difference between revisions of "CheA"
| Line 61: | Line 61: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' autophosphorylation, phosphorylation of [[CheY]] | + | * '''Catalyzed reaction/ biological activity:''' autophosphorylation, phosphorylation of [[CheY]] and [[CheB]] {{PubMed|11553614}} |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 79: | Line 79: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[CheA]]-[[McpB]] {{PubMed|19864420}}, [[CheA]]-[[CheC]] {{PubMed|11722727}}, [[CheA]]-[[CheY]] | + | * '''Interactions:''' [[CheA]]-[[McpB]] {{PubMed|19864420}}, [[CheA]]-[[CheC]] {{PubMed|11722727}}, [[CheA]]-[[CheY]] {{PubMed|11553614}} |
| − | |||
* '''Localization:''' membrane (according to Swiss-Prot) | * '''Localization:''' membrane (according to Swiss-Prot) | ||
| Line 136: | Line 135: | ||
<pubmed> 20122866 </pubmed> | <pubmed> 20122866 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>1938941,12123464,17908686,8866475,12094812,10094672,11722727,14651647, 9657996,8157612,15175317 9721285 17850253 </pubmed> | + | <pubmed>1938941,12123464,17908686,8866475,12094812,10094672,11722727,14651647, 9657996,8157612,15175317 9721285 17850253 11553614</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:05, 1 December 2010
- Description: two-component sensor kinase, chemotactic signal modulator
| Gene name | cheA |
| Synonyms | cheN |
| Essential | no |
| Product | two-component sensor kinase |
| Function | chemotactic signal modulator |
| MW, pI | 74 kDa, 4.452 |
| Gene length, protein length | 2013 bp, 671 aa |
| Immediate neighbours | cheB, cheW |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU16430
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
Categories containing this gene/protein
protein modification, transcription factors and their control, motility and chemotaxis, membrane proteins, phosphoproteins
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of CheY and CheB PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity:
- Interactions: CheA-McpB PubMed, CheA-CheC PubMed, CheA-CheY PubMed
- Localization: membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P29072
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Gerald L Hazelbauer, Wing-Cheung Lai
Bacterial chemoreceptors: providing enhanced features to two-component signaling.
Curr Opin Microbiol: 2010, 13(2);124-32
[PubMed:20122866]
[WorldCat.org]
[DOI]
(I p)
Original publications
