Difference between revisions of "FtsZ"
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| − | + | * '''Description:''' cell-division initiation protein (septum formation) <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ftsA]]'', ''[[bpr]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ftsA]]'', ''[[bpr]]'' | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+& | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB13402]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
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| − | |colspan="2" | '''Genetic context''' | + | |colspan="2" | '''Genetic context''' <br/> [[Image:ftsZ_context.gif]] |
| − | + | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | |
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__TOC__ | __TOC__ | ||
| − | + | <br/><br/> | |
=The gene= | =The gene= | ||
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==Reviews== | ==Reviews== | ||
| − | + | <pubmed> 19680248 19884039 17506674 15037301 </pubmed> | |
==FtsZ as antibacterial drug target== | ==FtsZ as antibacterial drug target== | ||
| − | + | <pubmed> 19583568 20410587 ,16174771, 20212044 20615583 </pubmed> | |
==Other original Publications== | ==Other original Publications== | ||
| − | + | <pubmed> 15288790, 15317782,12180929, 9364910,10323866, 19212404,15942012, 12007411,16420366, 16159787,10747015, 16796675,10322023,9495766,9287012,1569582,10878122,11395470,10449747,17662947,12368265,18284588,8600030,18588879,7592498, 19136590 , 19429628, 19141479 19843223 16484179 20199598 20566861 20711458 20807205 20933427 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 04:57, 24 November 2010
- Description: cell-division initiation protein (septum formation)
| Gene name | ftsZ |
| Synonyms | ts-1 |
| Essential | yes PubMed |
| Product | cell-division initiation protein (septum formation) |
| Function | formation of Z-ring |
| MW, pI | 40 kDa, 4.814 |
| Gene length, protein length | 1146 bp, 382 aa |
| Immediate neighbours | ftsA, bpr |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU15290
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ftsZ family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: Z ring formation is inhibited upon binding of MciZ to FtsZ
- Interactions: FtsZ-ZapA PubMed, FtsZ-EzrA PubMed, FtsZ-SpoIIE, FtsZ-FtsA, FtsZ-FtsZ PubMed, MciZ-FtsZ PubMed, FtsZ-SepF
- Localization:
Database entries
- UniProt: P17865
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody: available in the Jeff Errington lab
Labs working on this gene/protein
Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage
Your additional remarks
References
Reviews
FtsZ as antibacterial drug target
Other original Publications
