Difference between revisions of "TcyN"
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]'' {{PubMed|15668000}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' [[SigA]] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CymR]]: transcription repression {{PubMed|16109943}} | ||
| + | ** [[YtlI]]: transcription activation {{PubMed|16109943}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 118: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>15262924,10092453,16109943,12193636, </pubmed> | + | <pubmed>15262924,10092453,16109943,12193636, 15272571 15668000</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 22:29, 18 December 2009
- Description: cystine ABC transporter (ATP-binding protein)
| Gene name | tcyN |
| Synonyms | hisP, ytmN |
| Essential | no |
| Product | cystine ABC transporter (ATP-binding protein) |
| Function | cystine uptake |
| MW, pI | 29 kDa, 8.835 |
| Gene length, protein length | 777 bp, 259 aa |
| Immediate neighbours | ytmO, tcyM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29340
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 2Q0H (complex with ADP-Mg2+, Geobacillus stearothermophilus, 54% identity )
- UniProt: O34900
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
