Difference between revisions of "ParC"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[parE]]-[[parC]]'' {{PubMed|16267290}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** induced by DNA damage ([[LexA]]) {{PubMed|16267290}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[LexA]]: transcription repression | + | ** [[LexA]]: transcription repression {{PubMed|16267290}} |
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 19:56, 18 October 2009
- Description: subunit of DNA topoisomerase IV
| Gene name | parC |
| Synonyms | grlA |
| Essential | yes PubMed |
| Product | subunit of DNA topoisomerase IV |
| Function | chromosome segregation and compaction |
| MW, pI | 91 kDa, 6.307 |
| Gene length, protein length | 2418 bp, 806 aa |
| Immediate neighbours | parE, ynfC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU18100
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: topoisomerase gyrA/parC subunit family (according to Swiss-Prot)
- Paralogous protein(s): GyrA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot), Cytoplasm (Homogeneous) PubMed polar localization in actively growing cells PubMed
Database entries
- Structure: 1WP5 (C-terminal domain, Geobacillus stearothermophilus)
- UniProt: Q45066
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
