Difference between revisions of "RNA switch"
(→List of Bacillus subtilis RNAswitches) |
(→List of Bacillus subtilis RNAswitches) |
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* potential additional RNA switches | * potential additional RNA switches | ||
The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes. | The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes. | ||
| + | |||
** [http://rfam.sanger.ac.uk/family?acc=RF00379 ydaO-yuaA switch]: ''[[ydaO]], [[ktrA]]'' | ** [http://rfam.sanger.ac.uk/family?acc=RF00379 ydaO-yuaA switch]: ''[[ydaO]], [[ktrA]]'' | ||
| − | ** ykkC-yxkD switch: ''[[ykkC]], [[yxkD]]'' | + | ** [http://rfam.sanger.ac.uk/family?acc=RF00442 ykkC-yxkD switch]: ''[[ykkC]], [[yxkD]]'' |
** [http://rfam.sanger.ac.uk/family?acc=RF00080 yybP-ykoY switch]: ''[[yybP]]'', ''[[ykoY]]'' | ** [http://rfam.sanger.ac.uk/family?acc=RF00080 yybP-ykoY switch]: ''[[yybP]]'', ''[[ykoY]]'' | ||
| − | ** ylbH switch: ''[[ylbH]]'' | + | ** [http://rfam.sanger.ac.uk/family?acc=RF00516 ylbH switch]: ''[[ylbH]]'' |
| − | ** | + | ** [http://rfam.sanger.ac.uk/family?acc=RF00557 L10 leader]: ''[[rplJ]]'' |
** [http://rfam.sanger.ac.uk/family?acc=RF00555 L13 leader]: ''[[rplM]]'' | ** [http://rfam.sanger.ac.uk/family?acc=RF00555 L13 leader]: ''[[rplM]]'' | ||
| − | ** | + | ** L19 leader: ''[[rplS]]'' |
| − | ** | + | ** [http://rfam.sanger.ac.uk/family?acc=RF00558 L20 leader]: in front of the ''[[infC]]-[[rpmL]]-[[rplT]]'' operon |
| − | ** L21_leader | + | ** [http://rfam.sanger.ac.uk/family?acc=RF00559 L21_leader]:in front of the ''[[rplU]]-[[ysxB]]-[[rpmA]]'' operon |
==Important Reviews== | ==Important Reviews== | ||
<pubmed>15063848 , 19250859 ,19141470 , 17092822, 17764952 ,17381303, 16226486 , 16153177 , 15750802, 14523920 </pubmed> | <pubmed>15063848 , 19250859 ,19141470 , 17092822, 17764952 ,17381303, 16226486 , 16153177 , 15750802, 14523920 </pubmed> | ||
Revision as of 13:54, 7 July 2009
RNA switches are regulatory systems that rely on alternative mRNA structures.
RNA switches may be triggered by proteins, tRNAs (T-box), or metabolites (riboswitches)
List of Bacillus subtilis RNAswitches
- Protein-dependent RNA switches
- potential additional RNA switches
The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes.
- ydaO-yuaA switch: ydaO, ktrA
- ykkC-yxkD switch: ykkC, yxkD
- yybP-ykoY switch: yybP, ykoY
- ylbH switch: ylbH
- L10 leader: rplJ
- L13 leader: rplM
- L19 leader: rplS
- L20 leader: in front of the infC-rpmL-rplT operon
- L21_leader:in front of the rplU-ysxB-rpmA operon
Important Reviews
Michael D Dambach, Wade C Winkler
Expanding roles for metabolite-sensing regulatory RNAs.
Curr Opin Microbiol: 2009, 12(2);161-9
[PubMed:19250859]
[WorldCat.org]
[DOI]
(I p)
Tina M Henkin
Riboswitch RNAs: using RNA to sense cellular metabolism.
Genes Dev: 2008, 22(24);3383-90
[PubMed:19141470]
[WorldCat.org]
[DOI]
(P p)
Catherine A Wakeman, Wade C Winkler, Charles E Dann
Structural features of metabolite-sensing riboswitches.
Trends Biochem Sci: 2007, 32(9);415-24
[PubMed:17764952]
[WorldCat.org]
[DOI]
(P p)
Irnov, A Kertsburg, W C Winkler
Genetic control by cis-acting regulatory RNAs in Bacillus subtilis: general principles and prospects for discovery.
Cold Spring Harb Symp Quant Biol: 2006, 71;239-49
[PubMed:17381303]
[WorldCat.org]
[DOI]
(P p)
Frank J Grundy, Tina M Henkin
From ribosome to riboswitch: control of gene expression in bacteria by RNA structural rearrangements.
Crit Rev Biochem Mol Biol: 2006, 41(6);329-38
[PubMed:17092822]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler
Riboswitches and the role of noncoding RNAs in bacterial metabolic control.
Curr Opin Chem Biol: 2005, 9(6);594-602
[PubMed:16226486]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler, Ronald R Breaker
Regulation of bacterial gene expression by riboswitches.
Annu Rev Microbiol: 2005, 59;487-517
[PubMed:16153177]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler
Metabolic monitoring by bacterial mRNAs.
Arch Microbiol: 2005, 183(3);151-9
[PubMed:15750802]
[WorldCat.org]
[DOI]
(P p)
Frank J Grundy, Tina M Henkin
Regulation of gene expression by effectors that bind to RNA.
Curr Opin Microbiol: 2004, 7(2);126-31
[PubMed:15063848]
[WorldCat.org]
[DOI]
(P p)
Wade C Winkler, Ronald R Breaker
Genetic control by metabolite-binding riboswitches.
Chembiochem: 2003, 4(10);1024-32
[PubMed:14523920]
[WorldCat.org]
[DOI]
(P p)
