ykkC

ykkC
168

putative guanidine exporter

Locus
BSU_13090
Molecular weight
11.78 kDa
Isoelectric point
5.36
Protein length
112 aaSequenceBlast
Gene length
339 bpSequenceBlast
Function
export/ detoxification of guanidine
Product
subunit of guanidine exporter
Essential
no
Synonyms
ykkC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2076 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,376,517  1,376,855
The protein
Protein family
paired small multidrug resistance  protein family (PSMR family) PubMed
drug/metabolite transporter (DMT) superfamily (according to UniProt)
Small multidrug resistance (SMR) (TC 2.A.7.1) family (according to UniProt)
Structure
5U3G (PDB) (the riboswitch from Dickeya dadantii, bound to guanidinium) PubMed
P49856 (AlphaFold)
Localization
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
ykkC-ykkD
Description
PubMed
Regulation
induced in the presence of guanidine (ykkC riboswitch) PubMed
Regulatory mechanism
YkkC riboswitch: RNA switch, PubMed, in YkkC riboswitch regulon
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ykkC→ykkD

2025-03-15 14:38:30

ghost

60

12ef4a40f3191d055e1518a030274c88ec540d1a

CFA7D4F021B5D5A483940692B621927D162FE138

Biological materials
Mutant
MGNA-A747 (ykkC::erm), available at the NBRP B. subtilis, Japan
BKE13090 (ykkC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTGAGTCATTCCTTTC,  downstream forward: _UP4_GAGGAAAAAGGAGGCGAGGC
BKK13090 (ykkC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTGAGTCATTCCTTTC,  downstream forward: _UP4_GAGGAAAAAGGAGGCGAGGC
References
Reviews
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Original Publications
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5FD89F65E481CDC33B10A58C12C3168B929917ED

Page visits: 2118

Time of last update: 2025-03-31 07:30:37

Author of last update: Melvin.boenninger