Difference between revisions of "CssR"
| Line 95: | Line 95: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed under conditions of secretion stress ([[CssR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12270824 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CssR]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/12270824 PubMed] | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 16:28, 11 June 2009
- Description: two-component response regulator, control of cellular responses to protein secretion stress
| Gene name | cssR |
| Synonyms | yvqA |
| Essential | no |
| Product | two-component response regulator |
| Function | control of cellular responses to protein secretion stress |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 26 kDa, 5.071 |
| Gene length, protein length | 675 bp, 225 aa |
| Immediate neighbours | htrB, cssS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU33010
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpR family of two-component response regulators
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: O32192
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Darmon E, Noone D, Masson A, Bron S, Kuipers OP, Devine KM, van Dijl JM. (2002) A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis. J Bacteriol. 184(20): 5661-71. PubMed
- Hyyryläinen HL, Bolhuis A, Darmon E, Muukkonen L, Koski P, Vitikainen M, Sarvas M, Prágai Z, Bron S, van Dijl JM, Kontinen VP. (2001) A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress. Mol Microbiol. 41(5): 1159-72. PubMed
