Difference between revisions of "OdhA"
Line 54: | Line 54: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO<sub>2</sub> (according to Swiss-Prot) |
* '''Protein family:''' 2-oxoacid dehydrogenase family (according to Swiss-Prot) | * '''Protein family:''' 2-oxoacid dehydrogenase family (according to Swiss-Prot) |
Revision as of 22:23, 23 May 2009
- Description: 2-oxoglutarate dehydrogenase (E1 subunit)
Gene name | odhA |
Synonyms | citK |
Essential | no |
Product | 2-oxoglutarate dehydrogenase (E1 subunit) |
Function | TCA cycle |
MW, pI | 105 kDa, 5.871 |
Gene length, protein length | 2823 bp, 941 aa |
Immediate neighbours | yojO, odhB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2 (according to Swiss-Prot)
- Protein family: 2-oxoacid dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P23129
- KEGG entry: BSU19370
- E.C. number: 1.2.4.2
Additional information
Expression and regulation
- Sigma factor: SigA
- Regulation: constitutive
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP671 (spc), GP665 (aphA3), GP684 (cat), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed