LicA

• Description: lichenan-specific phosphotransferase system, EIIA component
  
  

Gene name	licA
Synonyms	celC
Essential	no
Product	lichenan-specific phosphotransferase system, EIIA component
Function	lichenan uptake and phosphorylation
MW, pI	12 kDa, 4.641
Gene length, protein length	330 bp, 110 aa
Immediate neighbours	licH, licC
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [2]

• E.C. number: 2.7.1.69

Expression and regulation

• Operon: licB-licC-licA-licH PubMed

• Sigma factor: SigA PubMed

• Regulation: repressed by glucose (CcpA) PubMed, carbon catabolite repression, induction by oligomeric ß-glucosides PubMed

• Regulatory mechanism: catabolite repression: repression by CcpA, induction: transcription activation by the PRD-type regulator LicR PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
2. Tobisch, S., P. Glaser, S. Krüger, and M. Hecker. 1997. Identification and characterization of a new ß-glucoside utilization system in Bacillus subtilis. J. Bacteriol. 179:496-506. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed