Revision as of 12:14, 23 February 2009

Description: inhibitor of pro-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-SigK processing

Caution: The sequence for this gene in SubtiList contains errors
Gene name	bofA
Caution: The sequence for this gene in SubtiList contains errors
Synonyms
Caution: The sequence for this gene in SubtiList contains errors
Essential	no
Caution: The sequence for this gene in SubtiList contains errors
Product
Caution: The sequence for this gene in SubtiList contains errors
Function	inhibition of the pro-	Caution: The sequence for this gene in SubtiList contains errors
Caution: The sequence for this gene in SubtiList contains errors
Caution: The sequence for this gene in SubtiList contains errors
MW, pI	8 kDa, 9.32
Caution: The sequence for this gene in SubtiList contains errors
Gene length, protein length	261 bp, 87 aa
Caution: The sequence for this gene in SubtiList contains errors
Immediate neighbours	yaaL, [[rrnA-	Caution: The sequence for this gene in SubtiList contains errors
Caution: The sequence for this gene in SubtiList contains errors
[http://subtiwiki.uni-	Caution: The sequence for this gene in SubtiList contains errors
[http://subtiwiki.uni-	Caution: The sequence for this gene in SubtiList contains errors
Caution: The sequence for this gene in SubtiList contains errors
Genetic context
Caution: The sequence for this gene in SubtiList contains errors

The gene

Basic information

Coordinates:

Phenotypes of a mutant

Database entries

DBTBS entry: [1]

SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

Catalyzed reaction/ biological activity:

Protein family:

Paralogous protein(s):

Extended information on the protein

Kinetic information:

Domains:

Modification:

Cofactor(s):

Effectors of protein activity:

Interactions: BofA-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-SpoIVB PubMed

Localization:

Database entries

Structure:

Swiss prot entry:

KEGG entry:

E.C. number:

Additional information

Expression and regulation

Operon: bofA PubMed

Sigma factor: SigE PubMed

Regulation: expressed during sporulation PubMed

Regulatory mechanism: repressed by SpoIIID PubMed

Additional information:

Biological materials

Mutant:

Expression vector:

lacZ fusion:

GFP fusion:

two-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-hybrid system:

Antibody:

Labs working on this gene/protein

Simon Cutting, London, UK homepage

Your additional remarks

References

Dong & Cutting (2004) The PDZ domain of the SpoIVB transmembrane signaling protein enables cis-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-trans interactions involving multiple partners leading to the activation of the pro- |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-sigmaK processing complex in Bacillus subtilis.J. Biol. Chem. 279: 43468- |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-43478. PubMed

Ireton & Grossman (1992 ) Interactions among mutations that cause altered timing of gene expression during sporulation in Bacillus subtilis. J. Bacteriol. 174: 3185-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-3195. PubMed

@@ Line 1: / Line 1: @@
-* '''Description:''' DNA polymerase III (gamma and tau subunits)DNA polymerase III (gamma and tau subunits)<br/><br/>
+* '''Description:''' inhibitor of pro-
+|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
+|-[[SigK]] processing<br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 6: / Line 8: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''dnaX''
+|''bofA''
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''dnaH, dna-
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
-|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-8132 ''
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
+|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || DNA polymerase III (gamma and tau subunits) (EC 2.7.7.7)
+|style="background:#ABCDEF;" align="center"| '''Product''' ||
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || DNA replication
+|style="background:#ABCDEF;" align="center"|'''Function''' || inhibition of the pro-
+|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
+|-sigma-
+|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
+|-K processing machinery
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 62 kDa, 5.488
+|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 9.32
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1689 bp, 563 aa
+|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 261 bp, 87 aa
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[scr]]'', ''[[yaaK]]''
+|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yaaL]]'', ''[[rrnA-
+|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
+|-16S]]''
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
@@ Line 42: / Line 48: @@
 |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-goettingen.de/dnaX_nucleotide.txt     Gene sequence      (+200bp)   ]'''
+|-goettingen.de/bofA_nucleotide.txt     Gene sequence      (+200bp)   ]'''
 |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-goettingen.de/dnaX_protein.txt Protein sequence]'''
+|-goettingen.de/bofA_protein.txt Protein sequence]'''
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
 |-
-|colspan="2" | '''Genetic context''' <br/> [[Image:dnaX_context.gif]]
+|colspan="2" | '''Genetic context''' <br/> [[Image:bofA_context.gif]]
 |-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
@@ Line 66: / Line 72: @@
 ===Phenotypes of a mutant ===
-essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
 === Database entries ===
-* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/dnaX.html]
+* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/bofA.html]
-* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10083]
+* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10087]
 === Additional information===
@@ Line 100: / Line 104: @@
 * '''Effectors of protein activity:'''
-* '''Interactions:''' [[DnaX]]-
+* '''Interactions:''' [[BofA]]-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-[[DnaB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/14757052 PubMed]
+|-[[SpoIVB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15292188 PubMed]
-* '''Localization:''' nucleoid region (mid-
-|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-cell spot) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
+* '''Localization:'''
 === Database entries ===
@@ Line 122: / Line 124: @@
 =Expression and regulation=
-* '''Operon:'''
+* '''Operon:''' ''bofA'' [http://www.ncbi.nlm.nih.gov/sites/entrez/1315731 PubMed]
-* '''Sigma factor:'''
+* '''Sigma factor:''' [[SigE]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1315731 PubMed]
-* '''Regulation:'''
+* '''Regulation:''' expressed during sporulation  [http://www.ncbi.nlm.nih.gov/sites/entrez/1315731 PubMed]
-* '''Regulatory mechanism:'''
+* '''Regulatory mechanism:''' repressed by [[SpoIIID]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1315731 PubMed]
 * '''Additional information:'''
 =Biological materials =
@@ Line 149: / Line 151: @@
 =Labs working on this gene/protein=
+Simon Cutting, London, UK [http://personal.rhul.ac.uk/uhba/009/bacillus/simon_cutting.html homepage]
 =Your additional remarks=
@@ Line 154: / Line 158: @@
 =References=
-# Haroniti et al. (2004) The clamp-
+# Dong & Cutting (2004) The PDZ domain of the SpoIVB transmembrane signaling protein enables cis-
-|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-loader-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-helicase interaction in ''Bacillus''. Atomic force microscopy reveals the structural organisation of the DnaB-
+|-trans interactions involving multiple partners leading to the activation of the pro-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-tau complex in ''Bacillus''.''J. Mol. Biol.'' '''336:''' 381-
+|-sigmaK processing complex in ''Bacillus subtilis''.''J. Biol. Chem.'' '''279:''' 43468-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-393. [http://www.ncbi.nlm.nih.gov/sites/entrez/14757052 PubMed]
+|-43478. [http://www.ncbi.nlm.nih.gov/sites/entrez/15292188 PubMed]
-# Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory ''Proteomics'' '''6:''' 2135-
+# Ireton & Grossman (1992 ) Interactions among mutations that cause altered timing of gene expression during sporulation in ''Bacillus subtilis''. ''J. Bacteriol.'' '''174:''' 3185-
 |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors'''
-|-2146. [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
+|-3195. [http://www.ncbi.nlm.nih.gov/sites/entrez/1315731 PubMed]

Difference between revisions of "Sandbox"

Revision as of 12:14, 23 February 2009

Contents

The gene

Basic information

Phenotypes of a mutant

Database entries

Additional information

The protein

Basic information/ Evolution

Extended information on the protein

Database entries

Additional information

Expression and regulation

Biological materials

Labs working on this gene/protein

Your additional remarks

References

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