Difference between revisions of "Sr1"

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* '''Synonyms:'''
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* '''Description:''' small regulatory RNA controlling [[AhrC]] expression<br/><br/>
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{| align="right" border="1" cellpadding="2"
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|-
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
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|''sr1''
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|-
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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|-
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || small regulatory RNA
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|-
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of arginine metabolism
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|-
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|style="background:#ABCDEF;" align="center"| '''pI, MW''' || not applicable
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|-
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|style="background:#ABCDEF;" align="center"| '''Gene size, protein size''' || aaa bp, not applicable
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|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[genA]]'', ''[[genB]]''
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|-
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt    Gene sequence      (+200bp)  ]'''
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|style="background:#FAF8CC;" align="center"|'''not applicable'''
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|-
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|colspan="2" | '''Genetic context''' <br/> [[Image:genE_context.gif]]
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|-
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|}
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__TOC__
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<br/><br/><br/><br/><br/><br/><br/><br/><br/><br/>
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* '''Description:''' small regulatory RNA controlling [[AhrC]] expression
 
 
 
 
=The gene=
 
=The gene=

Revision as of 18:59, 15 December 2008

  • Description: small regulatory RNA controlling AhrC expression

Gene name sr1
Synonyms
Essential no
Product small regulatory RNA
Function control of arginine metabolism
pI, MW not applicable
Gene size, protein size aaa bp, not applicable
Immediate neighbours genA, genB
Gene sequence (+200bp) not applicable
Genetic context
File:GenE context.gif












The gene

Basic information

  • Coordinates:
  • Gene length:

Phenotypes of a mutant

Database entries

  • DBTBS entry:

Additional information

Located between the slp and speA genes.


The RNA

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: hybridizes to ahrC mRNA and inhibits AhrC translation. PubMed

Extended information on the RNA

  • Kinetic information
  • Localization

Database entries

  • Structure:

Additional information

Information on the structure of the RNA can be found in Heidrich et al., 2006

Expression and regulation

  • Regulation: Repressed in the presence of glucose by CcpN PubMed
  • Regulatory mechanism: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • Antibody:


Labs working on this gene/protein

Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage

Your additional remarks

References

  1. Licht et al. (2005) Implication of CcpN in the regulation of a novel untranslated RNA (SR1) in Bacillus subtilis. Mol. Microbiol. 58: 189-206. PubMed
  2. Heidrich et al. (2006) The small untranslated RNA SR1 from the Bacillus subtilis genome is involved in the regulation of arginine catabolism. Mol. Microbiol. 62: 520-536. PubMed
  3. Heidrich et al. (2007) In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA. Nucl. Acids Res. 35: 4331-4346. PubMed
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