Difference between revisions of "Phosphorelay"
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=Back to [[categories]]= | =Back to [[categories]]= |
Revision as of 10:33, 15 September 2018
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see Table to the right |
Contents
- 1 The kinases
- 2 Proteins controlliing the activity of the kinases
- 3 The phosphotransferases
- 4 The ultimate target
- 5 Phosphatases controlling the phosphorelay (and peptides that modulate their activity)
- 6 Other protein controlling the activity of the phosphorelay
- 7 A mathematical model
- 8 Reviews
- 9 Important original publications
- 10 Back to categories
The phosphorelay is a complex variation of a two-component regulatory system. It includes phosphotransferases that transfer the phosphoryl group from the sensor kinases to the ultimate target. The sporulation initiation phosphorelay is the paradigm of this class of signal transduction systems.
The kinases
- KinA (controlled by Sda, SivA, BslA, KipI, and KipA)
- KinB (controlled by Sda, KbaA, and KapB)
- KinC
- KinD
- KinE
Proteins controlliing the activity of the kinases
The phosphotransferases
The ultimate target
Phosphatases controlling the phosphorelay (and peptides that modulate their activity)
- Spo0E: dephosphorylation of Spo0A
- YisI: dephosphorylation of Spo0A
- YnzD: dephosphorylation of Spo0A
- RapA, PhrA: dephosphorylation of Spo0F
- RapB: dephosphorylation of Spo0F
- RapE, PhrE: dephosphorylation of Spo0F
- RapH: dephosphorylation of Spo0F
- RapP: dephosphorylation of Spo0F PubMed
Other protein controlling the activity of the phosphorelay
A mathematical model
Reviews
Important original publications