Difference between revisions of "ValS"
Line 61: | Line 61: | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28090&redirect=T BSU28090] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/valS-folC.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/valS-folC.html] | ||
Line 95: | Line 96: | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28090&redirect=T BSU28090] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IYW 1IYW] (from ''Thermus thermophilus'', 41% identity, 60% similarity) {{PubMed|12554880}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IYW 1IYW] (from ''Thermus thermophilus'', 41% identity, 60% similarity) {{PubMed|12554880}} |
Revision as of 14:24, 2 April 2014
- Description: valyl-tRNA synthetase
Gene name | valS |
Synonyms | |
Essential | yes PubMed |
Product | valyl-tRNA synthetase |
Function | translation |
Gene expression levels in SubtiExpress: valS | |
Metabolic function and regulation of this protein in SubtiPathways: valS | |
MW, pI | 101 kDa, 4.868 |
Gene length, protein length | 2640 bp, 880 aa |
Immediate neighbours | folC, yszA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
translation, essential genes, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28090
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU28090
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) (according to Swiss-Prot)
- Protein family: ValS type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU28090
- UniProt: Q05873
- KEGG entry: [3]
- E.C. number: 6.1.1.9
Additional information
Expression and regulation
- Regulatory mechanism:
- T-box: riboswitch, transcription termination/antitermination PubMed
- Additional information:
- translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications