Difference between revisions of "CarB"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11240&redirect=T BSU11240]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/argCJBD-carAB-argF.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/argCJBD-carAB-argF.html]
Line 92: Line 93:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11240&redirect=T BSU11240]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JDB 1JDB] (from ''Escherichia coli'', 47% identity, 64% similarity) {{PubMed|10089390}}
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JDB 1JDB] (from ''Escherichia coli'', 47% identity, 64% similarity) {{PubMed|10089390}}

Revision as of 14:24, 2 April 2014

  • Description: carbamoyl-phosphate transferase-arginine subunit B)

Gene name carB
Synonyms cpa
Essential no
Product carbamoyl-phosphate transferase-arginine subunit B)
Function biosynthesis of arginine
Gene expression levels in SubtiExpress: carB
Interactions involving this protein in SubtInteract: CarB
Metabolic function and regulation of this protein in SubtiPathways:
carB
MW, pI 112 kDa, 4.712
Gene length, protein length 3090 bp, 1030 aa
Immediate neighbours carA, argF
Sequences Protein DNA DNA_with_flanks
Genetic context
CarB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CarB expression.png















Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, most abundant proteins

This gene is a member of the following regulons

AhrC regulon

The gene

Basic information

  • Locus tag: BSU11240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate (according to Swiss-Prot)
  • Protein family: carB family (according to Swiss-Prot)
  • Paralogous protein(s): PyrAB

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 1JDB (from Escherichia coli, 47% identity, 64% similarity) PubMed
  • KEGG entry: [3]

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References