Difference between revisions of "Fbp"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| + | ** specific activity: 0.203 µmol min<sup>-1</sup> (mg protein)<sup>-1</sup> {{PubMed|24571712}} | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fbp_4128029_4130044_1 fbp] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fbp_4128029_4130044_1 fbp] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|9696785}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9696785}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:37, 28 February 2014
- Description: fructose-1,6-bisphosphatase, involved in gluconeogenesis
| Gene name | fbp |
| Synonyms | fdp, yydE |
| Essential | no |
| Product | fructose-1,6-bisphosphatase |
| Function | gluconeogenesis |
| Gene expression levels in SubtiExpress: fbp | |
| Metabolic function and regulation of this protein in SubtiPathways: fbp | |
| MW, pI | 77 kDa, 5.601 |
| Gene length, protein length | 2013 bp, 671 aa |
| Immediate neighbours | yydF, yydD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40190
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate (according to Swiss-Prot)
- Protein family: FBPase class 3 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- specific activity: 0.203 µmol min-1 (mg protein)-1 PubMed
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q45597
- KEGG entry: [3]
- E.C. number: 3.1.3.11
Additional information
Expression and regulation
- Operon: fpb PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Michael Kohlstedt, Praveen K Sappa, Hanna Meyer, Sandra Maaß, Adrienne Zaprasis, Tamara Hoffmann, Judith Becker, Leif Steil, Michael Hecker, Jan Maarten van Dijl, Michael Lalk, Ulrike Mäder, Jörg Stülke, Erhard Bremer, Uwe Völker, Christoph Wittmann
Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective.
Environ Microbiol: 2014, 16(6);1898-917
[PubMed:24571712]
[WorldCat.org]
[DOI]
(I p)
Y Fujita, K Yoshida, Y Miwa, N Yanai, E Nagakawa, Y Kasahara
Identification and expression of the Bacillus subtilis fructose-1, 6-bisphosphatase gene (fbp).
J Bacteriol: 1998, 180(16);4309-13
[PubMed:9696785]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, E Freese
Isolation and properties of a Bacillus subtilis mutant unable to produce fructose-bisphosphatase.
J Bacteriol: 1981, 145(2);760-7
[PubMed:6257649]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, E Freese
Purification and properties of fructose-1,6-bisphosphatase of Bacillus subtilis.
J Biol Chem: 1979, 254(12);5340-9
[PubMed:221467]
[WorldCat.org]
(P p)
