Difference between revisions of "HtrB"

From SubtiWiki
Jump to: navigation, search
Line 37: Line 37:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/><br/><br/>
+
<br/><br/>
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
Line 62: Line 62:
  
 
=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
Line 80: Line 77:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
Line 112: Line 109:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 htrB] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 htrB] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 122: Line 119:
  
 
* '''Additional information:'''
 
* '''Additional information:'''
 +
** [[HtrB]] is subject to degradation by [[WprA]] and other extracellular proteases {{PubMed|24362423}}
  
 
=Biological materials =
 
=Biological materials =
Line 146: Line 144:
  
 
== Original publications ==
 
== Original publications ==
<pubmed>17600057,22307758,12270824, 22092710</pubmed>
+
<pubmed>17600057,22307758,12270824, 22092710 24362423</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:29, 16 January 2014

  • Description: membrane-anchored protein quality control protease, serine protease, response to secretion and heat stresses

Gene name htrB
Synonyms yvtA, yvtB
Essential no
Product serine protease
Function protein quality control
Gene expression levels in SubtiExpress: htrB
Metabolic function and regulation of this protein in SubtiPathways:
htrB
MW, pI 48 kDa, 4.632
Gene length, protein length 1374 bp, 458 aa
Immediate neighbours mrgA, cssR
Sequences Protein DNA DNA_with_flanks
Genetic context
YvtA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HtrB expression.png















Categories containing this gene/protein

proteolysis, heat shock proteins, membrane proteins

This gene is a member of the following regulons

CssR regulon

The gene

Basic information

  • Locus tag: BSU33000

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S1B family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:
  • Localization:
    • cell membrane (according to Swiss-Prot)
    • randomly distributed in foci throughout the cell surface PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: htrB (according to DBTBS)
  • Regulation:
    • expressed under conditions of secretion stress (CssR) PubMed
    • induced by rhamnolipids PubMed
  • Regulatory mechanism:
  • Additional information:
    • HtrB is subject to degradation by WprA and other extracellular proteases PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original publications