Difference between revisions of "Xpt"
| Line 60: | Line 60: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22070&redirect=T BSU22070] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/xpt-pbuX.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/xpt-pbuX.html] | ||
| Line 98: | Line 99: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22070&redirect=T BSU22070] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Y0B 1Y0B], [http://www.rcsb.org/pdb/explore.do?structureId=2FXV 2FXV] (complex with GMP), [http://www.rcsb.org/pdb/explore.do?structureId=1Y27 1Y27] (the riboswitch in complex with guanine) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Y0B 1Y0B], [http://www.rcsb.org/pdb/explore.do?structureId=2FXV 2FXV] (complex with GMP), [http://www.rcsb.org/pdb/explore.do?structureId=1Y27 1Y27] (the riboswitch in complex with guanine) | ||
Revision as of 14:01, 2 April 2014
- Description: xanthine phosphoribosyltransferase
| Gene name | xpt |
| Synonyms | |
| Essential | no |
| Product | xanthine phosphoribosyltransferase |
| Function | purine salvage and interconversion |
| Gene expression levels in SubtiExpress: xpt | |
| Metabolic function and regulation of this protein in SubtiPathways: xpt | |
| MW, pI | 20 kDa, 5.835 |
| Gene length, protein length | 582 bp, 194 aa |
| Immediate neighbours | pbuX, ypwA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22070
Phenotypes of a mutant
Database entries
- BsubCyc: BSU22070
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU22070
- UniProt: P42085
- KEGG entry: [3]
- E.C. number: 2.4.2.22
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulation:
- Regulatory mechanism:
- G-box: transcription termination/ antitermination (riboswitch) PubMed
- PurR: transcription repression (molecular inducer: PRPP) PubMed
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
