Difference between revisions of "DnaC"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2R6A 2R6A] (Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=2R6C 2R6C], [http://www.rcsb.org/pdb/explore.do?structureId=2R6D 2R6D], [http://www.rcsb.org/pdb/explore.do?structureId=2R6E 2R6E] | + | * '''Structure:''' |
| + | ** [http://www.rcsb.org/pdb/explore.do?structureId=2R6A 2R6A] (Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=2R6C 2R6C], [http://www.rcsb.org/pdb/explore.do?structureId=2R6D 2R6D], [http://www.rcsb.org/pdb/explore.do?structureId=2R6E 2R6E] | ||
| + | ** [http://www.rcsb.org/pdb/explore.do?structureId=4M4W 4M4W] (the [[DnaC]]-[[DnaI]]-[[DnaG]] complex) {{PubMed|24048025}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37469 P37469] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P37469 P37469] | ||
Revision as of 08:30, 23 September 2013
- Description: replicative DNA helicase, part of the replisome
| Gene name | dnaC |
| Synonyms | |
| Essential | yes PubMed |
| Product | replicative DNA helicase |
| Function | DNA replication |
| Gene expression levels in SubtiExpress: dnaC | |
| Interactions involving this protein in SubtInteract: DnaC | |
| MW, pI | 50 kDa, 4.548 |
| Gene length, protein length | 1362 bp, 454 aa |
| Immediate neighbours | yycE, yycD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
DNA replication, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40440
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: DnaB subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: Cytoplasm (Homogeneous) PubMed
Database entries
- Structure:
- UniProt: P37469
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: dnaC (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Geoffrey S Briggs, Wiep Klaas Smits, Panos Soultanas
Chromosomal replication initiation machinery of low-G+C-content Firmicutes.
J Bacteriol: 2012, 194(19);5162-70
[PubMed:22797751]
[WorldCat.org]
[DOI]
(I p)
Original publications
