yqaM

yqaM
168

similar to phage-related protein, skin-element

Locus
BSU_26260
Molecular weight
35.98 kDa
Isoelectric point
5.39
Protein length
286 aaSequenceBlast
Gene length
861 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
yqaM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG1484 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon, SknR regulon

Gene
Coordinates
2,693,597 → 2,694,457
Phenotypes of a mutant
overexpression of YqaM causes cell filamentation and abnormal chromosome segregation PubMed
overexpression of YqaM inhibits initiation DNA replication, perhaps due to the interaction with DnaC  PubMed
The protein
Structure
3ECC (PDB) (Aquifex aeolicus DnaC, C-terminus of YqaM, corresponds to aa 135 ... 277, 29% identity) PubMed
P45910 (AlphaFold)
Paralogous protein(s)
XkdC
Localization
Cytoplasm (Homogeneous) PubMed
Expression and Regulation
Operons
Genes
yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN
Description
PubMed
Regulation
not expressed during normal growth (SknR) PubMed
Regulatory mechanism
SknR: repression, PubMed, in sknR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
A ncRNA is predicted between yqaJ and yqaI PubMed
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yqaF→yqaN

2025-03-02 01:08:50

Jstuelk

68

e470304f15cd37310c8ed727bb7e0f54ad7c2747

7A6791A58F019385F6E775ED3FB2F9370F7F8AD1

Biological materials
Mutant
BKE26260 (ΔyqaM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCCTTACAATAAGGACAAT,  downstream forward: _UP4_CAATTAAATCATAGGTTAGG
BKK26260 (ΔyqaM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCCTTACAATAAGGACAAT,  downstream forward: _UP4_CAATTAAATCATAGGTTAGG
References
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Time of last update: 2025-03-12 21:28:22

Author of last update: Jstuelk