Difference between revisions of "DapA"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[cell wall synthesis]]}}, | ||
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
| + | {{SubtiWiki category|[[Biosynthesis of cell wall components]]}}, | ||
{{SubtiWiki category|[[sporulation proteins]]}}, | {{SubtiWiki category|[[sporulation proteins]]}}, | ||
{{SubtiWiki category|[[essential genes]]}} | {{SubtiWiki category|[[essential genes]]}} | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H<sub>2</sub>O (according to Swiss-Prot) | + | * '''Catalyzed reaction/ biological activity:''' L-aspartate 4-semialdehyde + pyruvate = L-2,3-dihydrodipicolinate + 2 H<sub>2</sub>O (according to Swiss-Prot) |
* '''Protein family:''' DHDPS family (according to Swiss-Prot) | * '''Protein family:''' DHDPS family (according to Swiss-Prot) | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapA_1748368_1749240_1 dapA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapA_1748368_1749240_1 dapA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
** ''[[spoVFA]]'': [[SigK]] {{PubMed|15699190,8098035}} | ** ''[[spoVFA]]'': [[SigK]] {{PubMed|15699190,8098035}} | ||
** ''[[asd]]'': [[SigA]] {{PubMed|8098035}} | ** ''[[asd]]'': [[SigA]] {{PubMed|8098035}} | ||
Revision as of 11:43, 5 January 2014
- Description: dihydrodipicolinate synthase
| Gene name | dapA |
| Synonyms | |
| Essential | yes PubMed |
| Product | dihydrodipicolinate synthase |
| Function | biosynthesis of lysine and peptidoglycan |
| Gene expression levels in SubtiExpress: dapA | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 30 kDa, 4.928 |
| Gene length, protein length | 870 bp, 290 aa |
| Immediate neighbours | dapG, rnjB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, sporulation proteins, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16770
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-aspartate 4-semialdehyde + pyruvate = L-2,3-dihydrodipicolinate + 2 H2O (according to Swiss-Prot)
- Protein family: DHDPS family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: Q04796
- KEGG entry: [3]
- E.C. number: 4.2.1.52
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
