GntR

• Description: transcriptional repressor of the gntR-gntK-gntP-gntZ operon
  
  

Gene name	gntR
Synonyms
Essential	no
Product	transcriptional repressor of the gluconate operon
Function	regulation of gluconate utilization
Gene expression levels in SubtiExpress: gntR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	28 kDa, 5.26
Gene length, protein length	729 bp, 243 aa
Immediate neighbours	yxaA, gntK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, GntR regulon

The GntR regulon:

• gntR-gntK-gntP-gntZ

The gene

Basic information

• Locus tag: BSU40050

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: gluconate acts as molecular inducer

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P10585

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gntR-gntK-gntP-gntZ PubMed1PubMed2

• Expression browser: gntR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by gluconate (GntR) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • GntR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed