Difference between revisions of "RocR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || transcriptional activator of arginine utilization operons | |style="background:#ABCDEF;" align="center"|'''Function''' || transcriptional activator of arginine utilization operons | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40350 rocR] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RocR RocR] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RocR RocR] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rocD]]'', ''[[yyzO]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rocD]]'', ''[[yyzO]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40350 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40350 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40350 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:rocR_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:rocR_context.gif]] | ||
Revision as of 15:19, 13 May 2013
- Description: transcriptional activator of arginine utilization operons
| Gene name | rocR |
| Synonyms | |
| Essential | no |
| Product | transcriptional activator |
| Function | transcriptional activator of arginine utilization operons |
| Gene expression levels in SubtiExpress: rocR | |
| Interactions involving this protein in SubtInteract: RocR | |
| Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate | |
| MW, pI | 52.6 kDa, 6.08 |
| Gene length, protein length | 1383 bp, 461 amino acids |
| Immediate neighbours | rocD, yyzO |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control
- see also: glutamate metabolism
This gene is a member of the following regulons
The RocR regulon
The gene
Basic information
- Locus tag: BSU40350
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation at SigL-dependent promoters of rocABC, rocDEF, and rocG
- Protein family: Sigma-54 interacting transcription activator
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Sigma-54 factor interaction domain (143–372)
- 2x nucleotid-binding domain (171–178),(233–242)
- HTH motif (434–453)
- Modification:
- Cofactor(s): ornithine or citrulline are required for RocR-dependent transcription activation PubMed
- Effectors of protein activity:
- Interactions:
- RocR-SigL
Database entries
- Structure:
- UniProt: P38022
- KEGG entry: [3]
Additional information
Expression and regulation
- Operon: rocR (according to DBTBS)
- Regulatory mechanism: autorepression
- Additional information:
Biological materials
- Mutant: QB5533 (aphA3), from Michel Debarbouille, available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- Antibody:
Labs working on this gene/protein
Michel Debarbouille, Pasteur Institute, Paris, France Homepage
Your additional remarks
References
