Difference between revisions of "TatCD"
| Line 109: | Line 109: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[phoD]]-[[tatAD]]-[[tatCD]]'' {{PubMed|22383849}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tatCD_286048_286776_1 tatCD] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tatCD_286048_286776_1 tatCD] {{PubMed|22383849}} | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10094677}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 148: | Line 148: | ||
<pubmed> 22683878 </pubmed> | <pubmed> 22683878 </pubmed> | ||
== Original publications == | == Original publications == | ||
| − | <pubmed>11007775,15554971,22544248,11007775, 19383693, 19395490 19616508 </pubmed> | + | <pubmed>11007775,15554971,22544248,11007775, 19383693, 19395490 19616508 22383849 10094677</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:19, 28 November 2012
- Description: component of the TatAdCd twin-arginine translocase
| Gene name | tatCD |
| Synonyms | ycbT |
| Essential | no |
| Product | component of the twin-arginine translocation pathway |
| Function | TAT protein secretion |
| Gene expression levels in SubtiExpress: tatCD | |
| Interactions involving this protein in SubtInteract: TatCD | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 27 kDa, 9.342 |
| Gene length, protein length | 735 bp, 245 aa |
| Immediate neighbours | tatAD, pcp |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
phosphate metabolism, protein secretion, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU02640
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Protein family: tatC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: P42252
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Oscar Kuipers, University of Groningen, The Netherlands Homepage
Your additional remarks
References
Reviews
Tracy Palmer, Ben C Berks
The twin-arginine translocation (Tat) protein export pathway.
Nat Rev Microbiol: 2012, 10(7);483-96
[PubMed:22683878]
[WorldCat.org]
[DOI]
(I e)
Original publications
Carmine G Monteferrante, Jacopo Baglieri, Colin Robinson, Jan Maarten van Dijl
TatAc, the third TatA subunit of Bacillus subtilis, can form active twin-arginine translocases with the TatCd and TatCy subunits.
Appl Environ Microbiol: 2012, 78(14);4999-5001
[PubMed:22544248]
[WorldCat.org]
[DOI]
(I p)
Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849]
[WorldCat.org]
[DOI]
(I p)
Olga V Nolandt, Torsten H Walther, Siegmar Roth, Jochen Bürck, Anne S Ulrich
Structure analysis of the membrane protein TatC(d) from the Tat system of B. subtilis by circular dichroism.
Biochim Biophys Acta: 2009, 1788(10);2238-44
[PubMed:19616508]
[WorldCat.org]
[DOI]
(P p)
Anja N J A Ridder, Esther J de Jong, Jan D H Jongbloed, Oscar P Kuipers
Subcellular localization of TatAd of Bacillus subtilis depends on the presence of TatCd or TatCy.
J Bacteriol: 2009, 191(13);4410-8
[PubMed:19395490]
[WorldCat.org]
[DOI]
(I p)
Robyn T Eijlander, Magdalena A Kolbusz, Erwin M Berendsen, Oscar P Kuipers
Effects of altered TatC proteins on protein secretion efficiency via the twin-arginine translocation pathway of Bacillus subtilis.
Microbiology (Reading): 2009, 155(Pt 6);1776-1785
[PubMed:19383693]
[WorldCat.org]
[DOI]
(P p)
Jan D H Jongbloed, Ulrike Grieger, Haike Antelmann, Michael Hecker, Reindert Nijland, Sierd Bron, Jan Maarten van Dijl
Two minimal Tat translocases in Bacillus.
Mol Microbiol: 2004, 54(5);1319-25
[PubMed:15554971]
[WorldCat.org]
[DOI]
(P p)
J D Jongbloed, U Martin, H Antelmann, M Hecker, H Tjalsma, G Venema, S Bron, J M van Dijl, J Müller
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
J Biol Chem: 2000, 275(52);41350-7
[PubMed:11007775]
[WorldCat.org]
[DOI]
(P p)
S Eder, W Liu, F M Hulett
Mutational analysis of the phoD promoter in Bacillus subtilis: implications for PhoP binding and promoter activation of Pho regulon promoters.
J Bacteriol: 1999, 181(7);2017-25
[PubMed:10094677]
[WorldCat.org]
[DOI]
(P p)
