Difference between revisions of "AlsS"
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|style="background:#ABCDEF;" align="center"|'''Function''' || overflow metabolism | |style="background:#ABCDEF;" align="center"|'''Function''' || overflow metabolism | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36010 alsS] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[alsD]]'', ''[[alsR]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[alsD]]'', ''[[alsR]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36010 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36010 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36010 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:alsS_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:alsS_context.gif]] | ||
Revision as of 15:01, 13 May 2013
- Description: acetolactate synthase
| Gene name | alsS |
| Synonyms | |
| Essential | no |
| Product | acetolactate synthase |
| Function | overflow metabolism |
| Gene expression levels in SubtiExpress: alsS | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 61 kDa, 5.164 |
| Gene length, protein length | 1713 bp, 571 aa |
| Immediate neighbours | alsD, alsR |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
AlsR regulon, Rex regulon, stringent response
The gene
Basic information
- Locus tag: BSU36010
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2 pyruvate = 2-acetolactate + CO2 (according to Swiss-Prot)
- Protein family: TPP enzyme family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q04789
- KEGG entry: [3]
- E.C. number: 2.2.1.6
Additional information
Expression and regulation
- Regulation:
Note: since acetate formation requires ackA activation by CcpA there is an indirect effect of CcpA on the alsSD operon: the operon is not expressed in ccpA mutants
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
