Difference between revisions of "YcnJ"
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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{{SubtiWiki regulon|[[YcnK regulon]]}} | {{SubtiWiki regulon|[[YcnK regulon]]}} | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ycnJ_446801_448426_-1 ycnJ] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ycnJ_446801_448426_-1 ycnJ] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''Sigma factor:''' [[SigA]] {{PubMed|22904286}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** induced by copper limitation ([[YcnK]]) {{PubMed|22904286,19168619}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[YcnK]]: transcription repression | + | ** [[YcnK]]: transcription repression {{PubMed|22904286,19168619}} |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 08:14, 23 August 2012
- Description: copper transporter
| Gene name | ycnJ |
| Synonyms | |
| Essential | no |
| Product | copper transporter |
| Function | uptake of copper |
| Gene expression levels in SubtiExpress: ycnJ | |
| MW, pI | 59 kDa, 10.098 |
| Gene length, protein length | 1623 bp, 541 aa |
| Immediate neighbours | ycnI, ycnK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03950
Phenotypes of a mutant
growth-defective under copper-limiting conditions PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: uptake of copper PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane PubMed
Database entries
- Structure:
- UniProt: C0SP95
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
Kazutake Hirooka, Takayosh Edahiro, Kosuke Kimura, Yasutaro Fujita
Direct and indirect regulation of the ycnKJI operon involved in copper uptake through two transcriptional repressors, YcnK and CsoR, in Bacillus subtilis.
J Bacteriol: 2012, 194(20);5675-87
[PubMed:22904286]
[WorldCat.org]
[DOI]
(I p)
Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849]
[WorldCat.org]
[DOI]
(I p)
Shashi Chillappagari, Marcus Miethke, Hein Trip, Oscar P Kuipers, Mohamed A Marahiel
Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis.
J Bacteriol: 2009, 191(7);2362-70
[PubMed:19168619]
[WorldCat.org]
[DOI]
(I p)
