Difference between revisions of "SkfC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || may be involved in spore killing
 
|style="background:#ABCDEF;" align="center"|'''Function''' || may be involved in spore killing
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU01935 skfC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01935 skfC]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 8.146   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 8.146   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[skfB]]'', ''[[skfE]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[skfB]]'', ''[[skfE]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAX52541&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01935 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01935 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01935 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ybcS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ybcS_context.gif]]

Revision as of 12:01, 13 May 2013

  • Description: may be involved in spore killing

Gene name skfC
Synonyms ybcS
Essential no
Product unknown
Function may be involved in spore killing
Gene expression levels in SubtiExpress: skfC
MW, pI 56 kDa, 8.146
Gene length, protein length 1488 bp, 496 aa
Immediate neighbours skfB, skfE
Sequences Protein DNA Advanced_DNA
Genetic context
YbcS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SkfC expression.png
























Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

AbrB regulon, PhoP regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU01935

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
    • induced by phosphate starvation (PhoP) PubMed
  • Additional information: Northern blotting during during phosphate limitation showed an intense 0.25 kb skfA-specific transcript, and a weaker 6.5 kb skfA-skfB-skfC-skfE-skfF-skfG-skfH transcript. PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377] [WorldCat.org] [DOI] (I p)

Original Publications