Difference between revisions of "MenB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of menaquinone | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of menaquinone | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30800 menB] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/menaquinone.html Menaquinone]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/menaquinone.html Menaquinone]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[menE]]'', ''[[ytxM]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[menE]]'', ''[[ytxM]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30800 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30800 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30800 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:menB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:menB_context.gif]] | ||
Revision as of 13:41, 13 May 2013
- Description: naphthoate synthase
| Gene name | menB |
| Synonyms | |
| Essential | yes PubMed |
| Product | naphthoate synthase |
| Function | biosynthesis of menaquinone |
| Gene expression levels in SubtiExpress: menB | |
| Metabolic function and regulation of this protein in SubtiPathways: Menaquinone | |
| MW, pI | 29 kDa, 5.343 |
| Gene length, protein length | 813 bp, 271 aa |
| Immediate neighbours | menE, ytxM |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, essential genes, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30800
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: o-succinylbenzoyl-CoA = CoA + 1,4-dihydroxy-2-naphthoate (according to Swiss-Prot)
- Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-78 and Arg-269 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1RJM (from Mycobacterium tuberculosis, 48% identity, 61% similarity)
- UniProt: P23966
- KEGG entry: [3]
- E.C. number: 4.1.3.36
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
