GlcP

• Description: probable glucose/mannose:H+ symporter
  
  

Gene name	glcP
Synonyms	yhjI
Essential	no
Product	probable glucose/mannose:H+ symporter
Function	unknown
Gene expression levels in SubtiExpress: glcP
MW, pI	44 kDa, 8.767
Gene length, protein length	1203 bp, 401 aa
Immediate neighbours	yhjH, ntdC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other

This gene is a member of the following regulons

NtdR regulon

The gene

Basic information

• Locus tag: BSU10520

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O07563

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ntdA-ntdB-ntdC-glcP PubMed

• Expression browser: glcP PubMed

• Sigma factor: SigA PubMed

• Regulation: induced by 3,3'-neotrehalosadiamine (NtdR) PubMed

• Regulatory mechanism: NtdR: positive regulator PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256] [WorldCat.org] [DOI] (I p)

Original publications

Takashi Inaoka, Takenori Satomura, Yasutaro Fujita, Kozo Ochi
Novel gene regulation mediated by overproduction of secondary metabolite neotrehalosadiamine in Bacillus subtilis.
FEMS Microbiol Lett: 2009, 291(2);151-6
[PubMed:19087206] [WorldCat.org] [DOI] (I p)

Takashi Inaoka, Kozo Ochi
Glucose uptake pathway-specific regulation of synthesis of neotrehalosadiamine, a novel autoinducer produced in Bacillus subtilis.
J Bacteriol: 2007, 189(1);65-75
[PubMed:17056753] [WorldCat.org] [DOI] (P p)

Takashi Inaoka, Kosaku Takahashi, Hiroshi Yada, Mitsuru Yoshida, Kozo Ochi
RNA polymerase mutation activates the production of a dormant antibiotic 3,3'-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis.
J Biol Chem: 2004, 279(5);3885-92
[PubMed:14612444] [WorldCat.org] [DOI] (P p)

I T Paulsen, S Chauvaux, P Choi, M H Saier
Characterization of glucose-specific catabolite repression-resistant mutants of Bacillus subtilis: identification of a novel hexose:H+ symporter.
J Bacteriol: 1998, 180(3);498-504
[PubMed:9457850] [WorldCat.org] [DOI] (P p)