Difference between revisions of "SkfC"

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* '''Description:''' may be involved in spore killing <br/><br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || may be involved in spore killing
 
|style="background:#ABCDEF;" align="center"|'''Function''' || may be involved in spore killing
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU01935 skfC]
 
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 8.146   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 8.146   
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|colspan="2" | '''Genetic context''' <br/> [[Image:ybcS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ybcS_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=skfC_215404_216894_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:skfC_expression.png|500px]]
 
 
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* '''Operon:''' ''[[skfA]]-[[skfB]]-[[skfC]]-[[skfE]]-[[skfF]]-[[skfG]]-[[skfH]]'' [http://www.ncbi.nlm.nih.gov/pubmed/16816204 PubMed]
 
* '''Operon:''' ''[[skfA]]-[[skfB]]-[[skfC]]-[[skfE]]-[[skfF]]-[[skfG]]-[[skfH]]'' [http://www.ncbi.nlm.nih.gov/pubmed/16816204 PubMed]
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=skfC_215404_216894_1 skfC] {{PubMed|22383849}}
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/pubmed/16452424 PubMed]
 
 
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/pubmed/16452424 PubMed]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 10:36, 7 August 2012

  • Description: may be involved in spore killing

Gene name skfC
Synonyms ybcS
Essential no
Product unknown
Function may be involved in spore killing
MW, pI 56 kDa, 8.146
Gene length, protein length 1488 bp, 496 aa
Immediate neighbours skfB, skfE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbcS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

AbrB regulon, PhoP regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU01935

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
    • induced by phosphate starvation (PhoP) PubMed
  • Additional information: Northern blotting during during phosphate limitation showed an intense 0.25 kb skfA-specific transcript, and a weaker 6.5 kb skfA-skfB-skfC-skfE-skfF-skfG-skfH transcript. PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377] [WorldCat.org] [DOI] (I p)

Original Publications