ComN

• Description: mediates post-transcriptional control of comE operon expression
  
  

Gene name	comN
Synonyms	yrzD
Essential	no
Product	post-transcriptional regulator of comE expression
Function	regulation of competence and DNA uptake
Gene expression levels in SubtiExpress: comN
Interactions involving this protein in SubtInteract: ComN
MW, pI	11 kDa, 4.622
Gene length, protein length	294 bp, 98 aa
Immediate neighbours	secDF, spoVB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, membrane proteins

The gene

Basic information

• Locus tag: BSU27660

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • post-transcriptional control of comEA expression PubMed
  • promotes the accumulation of its target comEA mRNA to septal and polar sites PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • DivIVA-ComN PubMed

• Localization:
  • localizes to the division site and cell poles in a DivIVA dependent fashion PubMed

Database entries

• Structure:

• UniProt: O32049

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: comN PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Valquiria Tiago dos Santos, Alexandre W Bisson-Filho, Frederico J Gueiros-Filho
DivIVA-mediated polar localization of ComN, a posttranscriptional regulator of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3661-9
[PubMed:22582279] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Teruo Tanaka
The Bacillus subtilis late competence operon comE is transcriptionally regulated by yutB and under post-transcription initiation control by comN (yrzD).
J Bacteriol: 2009, 191(3);949-58
[PubMed:19028902] [WorldCat.org] [DOI] (I p)