Difference between revisions of "RocR"
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| # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | ||
| # Ali, N. O., Bignon, J., Rapoport, G., and Débarbouillé, M. (2001) Regulation of the acetoin catabolic pathway is controlled by sigma L in Bacillus subtilis. J. Bacteriol. 183, 2497-2504. [http://www.ncbi.nlm.nih.gov/sites/entrez/11274109  PubMed] | # Ali, N. O., Bignon, J., Rapoport, G., and Débarbouillé, M. (2001) Regulation of the acetoin catabolic pathway is controlled by sigma L in Bacillus subtilis. J. Bacteriol. 183, 2497-2504. [http://www.ncbi.nlm.nih.gov/sites/entrez/11274109  PubMed] | ||
| − | # Belitsky BR, Sonenshein AL (1998) Role and regulation of Bacillus subtilis glutamate dehydrogenase genes. J Bacteriol 180:6298-6305. [http://www.ncbi.nlm.nih.gov/sites/entrez/ | + | # Belitsky BR, Sonenshein AL (1998) Role and regulation of Bacillus subtilis glutamate dehydrogenase genes. J Bacteriol 180:6298-6305. [http://www.ncbi.nlm.nih.gov/sites/entrez/9829940   PubMed] | 
| # Belitsky BR, Sonenshein, AL: (1999) An enhancer element located downstream of the major glutamate dehydrogenase gene of Bacillus subtilis. Proc Natl Acad Sci USA , 96:10290-10295. [http://www.ncbi.nlm.nih.gov/sites/entrez/10468601   PubMed] | # Belitsky BR, Sonenshein, AL: (1999) An enhancer element located downstream of the major glutamate dehydrogenase gene of Bacillus subtilis. Proc Natl Acad Sci USA , 96:10290-10295. [http://www.ncbi.nlm.nih.gov/sites/entrez/10468601   PubMed] | ||
| − | # Gardan R, Rapoport G, Débarbouillé M: Role of the transcriptional activator RocR in the arginine-degradation pathway of Bacillus subtilis. Mol Microbiol  | + | # Gardan R, Rapoport G, Débarbouillé M:(1997) Role of the transcriptional activator RocR in the arginine-degradation pathway of Bacillus subtilis. Mol Microbiol , 24:825-837. [http://www.ncbi.nlm.nih.gov/sites/entrez/9194709   PubMed] | 
| − | # Gardan R, Rapoport G, Débarbouillé M: Expression of the rocDEF operon involved in arginine catabolism in Bacillus subtilis. J Mol Biol  | + | # Gardan R, Rapoport G, Débarbouillé M: (1995) Expression of the rocDEF operon involved in arginine catabolism in Bacillus subtilis. J Mol Biol , 249:843-856. [http://www.ncbi.nlm.nih.gov/sites/entrez/7540694   PubMed] | 
Revision as of 10:01, 14 January 2009
-  Description:  	 transcriptional activator of arginine utilization operons 
| Gene name | rocR | 
| Synonyms | |
| Essential | no | 
| Product | transcriptional regulator | 
| Function | transcriptional activator of arginine utilization operons | 
| MW, pI | 52.6 kDa, 6.08 | 
| Gene length, protein length | 1383 bp, 461 amino acids | 
| Immediate neighbours | rocD, yyxA | 
| Gene sequence (+200bp) | Protein sequence | 
| Genetic context   | |
Contents
The gene
Basic information
- Coordinates: 4144771 - 4146153
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation at SigL-dependent promoters of rocABC, rocDEF, and rocG
- Protein family: Sigma-54 interacting transcription activator
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
-  Domains: 
- Sigma-54 factor interaction domain (143–372)
- 2x nucleotid-binding domain (171–178),(233–242)
- HTH motif (434–453)
 
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: RocR-SigL
- Localization:
Database entries
- Structure:
- Swiss prot entry: [3]
- KEGG entry: [4]
Additional information
Expression and regulation
- Operon: rocR
- Regulatory mechanism: autorepression
- Additional information:
Biological materials
Labs working on this gene/protein
Michel Debarbouille, Pasteur Institute, Paris, France Homepage
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
- Ali, N. O., Bignon, J., Rapoport, G., and Débarbouillé, M. (2001) Regulation of the acetoin catabolic pathway is controlled by sigma L in Bacillus subtilis. J. Bacteriol. 183, 2497-2504. PubMed
- Belitsky BR, Sonenshein AL (1998) Role and regulation of Bacillus subtilis glutamate dehydrogenase genes. J Bacteriol 180:6298-6305. PubMed
- Belitsky BR, Sonenshein, AL: (1999) An enhancer element located downstream of the major glutamate dehydrogenase gene of Bacillus subtilis. Proc Natl Acad Sci USA , 96:10290-10295. PubMed
- Gardan R, Rapoport G, Débarbouillé M:(1997) Role of the transcriptional activator RocR in the arginine-degradation pathway of Bacillus subtilis. Mol Microbiol , 24:825-837. PubMed
- Gardan R, Rapoport G, Débarbouillé M: (1995) Expression of the rocDEF operon involved in arginine catabolism in Bacillus subtilis. J Mol Biol , 249:843-856. PubMed

